Human CD36
BACKGROUND
Is an integral membrane glygoprotein belonging to the family of class B scaravenger receptors, which binds many ligands such as collagen, trombospondin , erytrocytes with malaria plasmodia, native and oxidized lypoproteins and phospholipids. On macrophages is part of a non opsonic receptor. Recently is has been implicated in the metabolisms of fatty acids and
glucose , cardiomyopathy and alzheimer’s disesase. For more information see dedicated website.
PRODUCT
Each vial contains the indicated amount of IgG (HPLC, Prot. A) in 0,1% gelatine and 0,05% NaN3.
SUBCLASS
Mouse IgM.
SPECIFICITY
Known also as gpIIIb; gpIV; OKM5-antigen; PASIV FAT,SCARB3, is expressed on:
platelets, microvascular endothelia, monocytes, erythroid precursor , machrophages, macrophage-
derived dendritic cells. It plays a role in the innate immunity to malaria. Mutations of CD36 are
known to be associated with resistence to platelets transfusion.
STORAGE
Store frozen, avoid repeated freeze-thawing. Stable for 2 yrs.
SHIPPING CONDITIONS
Room temperature.
RESEARCH USE
See references for described uses. This antibody is for laboratory research use only, not for human or in-vivo use.
APPLICATIONS
See enlisted references.
REFERENCES
1. Cell Immunol (1991) 137: 487.
2. Blood (1993) 82: 3637.
- Sku
- MP-AA-17
- Description
- CLONE NL07
- Product Options
# Option Price Download 1 HPLC, Prot. A - 150 µg €150,00 MP-AA-17